Japanese Encephalitis Virus NS1 Antibody
Cat# OANB00125-500UG
Size : 500ug
Brand : Aviva Systems Biology
Japanese Encephalitis Virus NS1 Antibody
Japanese Encephalitis Virus NS1 Antibody (OANB00125)
| Datasheets/Manuals | Printable datasheet for OANB00125 |
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| Predicted Species Reactivity | Viral |
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| Product Format | Phosphate Buffered Saline pH 7.4 |
| Clonality | Monoclonal |
| Clone | BD6.E6.G10.D11 |
| Isotype | IgG2b |
| Host | Mouse |
| Reconstitution and Storage | Store at +4C for up to three months, or at -20C for longer periods. Avoid repeated freeze/thaw cycles. |
| Immunogen | Recombinant Japanese Encephalitis virus NS1. |
| Purification | Affinity chromatography on protein G. |
| Concentration | Batch dependent. 1.0mg/ml. |
| Preservative | None present. |
| Specificity | This antibody is specific for the NS1 protein of Japanese Encephalitis virus, and does not cross-react with NS1 from other flaviviruses, including Dengue virus serotypes 1-4, Zika virus, Yellow Fever virus and West Nile virus. No cross-reactivity is seen with Chikungunya virus E1, E2 or C proteins. |
| Purity | >95% |
| Application Info | Direct ELISA |
| Description of Target | The NS1 protein is a major non-structural protein expressed by the Japanese Encephalitis Virus. The NS1 monomer is a glycosylated protein of approximately 45kD, which associates with lipids and forms a homodimer inside infected cells. It Is necessary for viral replication, and is also secreted into the extracellular space as a hexameric lipoprotein particle, which is involved in immune evasion and pathogenesis by interacting with components from both the innate and adaptive immune systems, as well as other host factors. |
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