Recombinant BVDV-2 Envelope Glycoprotein E2
Cat# DRA225-500ug
Size : 500ug
Brand : Novoprotein
Description Recombinant BVDV-2 Envelope Glycoprotein E2 is produced by our Mammalian expression system and the target gene is expressed with a 6His tag at the N-terminus.
Accession YP_009513240.1
Known As Envelope glycoprotein E2; E2 protein
Mol Mass 39.1 kDa
APMol Mass 43-60 kDa, reducing conditions
Formulation Description Supplied as a 0.2 μm filtered solution of PBS, pH7.4
Purity-SDS-PAGE 
Greater than 95% as determined by reducing SDS-PAGE. (QC verified) Purity-SEC-HPLC 
Greater than 95% as determined by SEC-HPLC.(QC verified) Storage - Reconstituted protein solution should be stored at ≤ -20°C.
- Stable for at least 24 months when stored as instructed.
Shipping The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Background Bovine viral diarrhea virus (BVDV) is a major pathogen that causes bovine viral diarrhea/mucosal disease (BVD-MD). BVDV is a single positive strand RNA virus, and according to the 5’UTR sequence, three genotypes (BVDV-1, BVDV-2 and BVDV-3) were identifed within BVDV strains. Among them, the highly pathogenic strain, BVDV-2, usually causes severe acute infection and hemorrhagic syndrome. Pestivirus envelope glycoprotein E2 is the most immunodominant protein and is of great importance for the development of vaccines and diagnostic tools. Glycoprotein E2 contains four domains (DA, DB, DC and DD), of which DA and DB are likely to be the most exposed on the virus surface. The N-terminus of E2, where the DA domain is located is the main target of neutralizing antibodies.