SOD1 Antibody - C-terminal region
Cat# ARP61114_P050
Size : 100ul
Brand : Aviva Systems Biology
SOD1 Antibody - C-terminal region (ARP61114_P050)
| Datasheets/Manuals | Printable datasheet for ARP61114_P050 |
|---|
| Tested Species Reactivity | Human, Mouse |
|---|---|
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C-terminal region of Human SOD1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 86%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 92% |
| Peptide Sequence | Synthetic peptide located within the following region: DVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLA |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | Catalog # AAP61114 |
| Gene Symbol | SOD1 |
|---|---|
| Alias Symbols | ALS, SOD, ALS1, IPOA, STAHP, hSod1, HEL-S-44, homodimer |
| NCBI Gene Id | 6647 |
| Protein Name | Superoxide dismutase [Cu-Zn] |
| Description of Target | SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis. |
| Uniprot ID | P00441 |
| Protein Accession # | NP_000445 |
| Nucleotide Accession # | NM_000454 |
| Protein Size (# AA) | 154 |
| Molecular Weight | 16 kDa |
| Protein Interactions | SOD1; CRYAB; UBC; SMAD2; HDAC6; GSH1; OPTN; PRDX5; AHCYL1; TIAL1; PRDX2; SPTBN1; SOD2; PPP2CA; PPIA; PLS3; PRDX1; NME2; NME1; Hspa4l; Hspa4; Hspa2; Hspa1b; Hsph1; Dnaja1; Hspa8; Hspa5; Ccs; UBE3A; COMMD1; Stub1; SUMO4; DYNLT1; AMFR; MARCH5; RNF19A; PSMD4; |
