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> TGF alpha Protein, Human, Recombinant V2

TGF alpha Protein, Human, Recombinant V2

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Cat# NB-64-128422-20ug

Size : 20ug

Brand : Neo Biotech


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TGF alpha Protein, Human, Recombinant V2

(Synonyms: transforming growth factor α, transforming growth factor alpha, TGF-α, TGFa, TFGA) Copy Product Info

Synonyms: transforming growth factor α, transforming growth factor alpha, TGF-α, TGFa, TFGA

Catalog No. TMPY-03958U Copy Product Info
TGF alpha Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P01135.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Bioactivity
ED 50 < 0.2 ng/ml, measured by Cell Proliferation Assay using BALB/c 3T3 cells, corresponding to a specific activity of ≥ 5.0 × 10^6 units/mg.
Description
TGF alpha Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P01135.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberP01135
ConstructionVal40-Ala89
Protein Purity
> 95% as determined by SDS-PAGE
Endotoxin< 0.2 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonymstransforming growth factor α, transforming growth factor alpha, TGF-α, TGFa, TFGA
Research Background
Transforming Growth Factor-alpha (TGF-α) , also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. It is expressed in monocytes, brain cells, keratinocytes and various tumor cells. TGF-α signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells. TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. The biological actions of TGF-α and EGF are similar. For instance, TGF-α and EGF bind to the same receptor. When TGF-α binds to EGFR it can initiate multiple cell proliferation events.
Chemical Properties
Molecular Weight5.8 kDa (Reducing conditions)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

TMPY-03958
Related Tags: TGF alpha Protein, Human, Recombinant V2 chemical structure | TGF alpha Protein, Human, Recombinant V2 molecular weight