EGFR probe for ISH CE/IVD - Breast and Gynecology pathology

EGFR probe for ISH CE/IVD - Breast and Gynecology pathology

 

The protein encoded by the EGFR gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Overexpression of the EGFR protein occurs across a wide range of different cancers. This upregulation appears to be frequently associated with adverse prognosis. Mutations of the EGFR gene occur in a range of cancers, and these often cause the overexpression of the EGFR protein.
The epidermal growth factor receptor (EGFR) is one of the major oncogenes identified in a variety of human malignancies including breast cancer (BC). EGFR-mutations have been studied in lung cancer for some years and are established as important markers in guiding therapy with tyrosine kinase inhibitors (TKIs).

 

 

Search result : 7 product found

Refine your search :

RUOCE / IVD
  • DIG-DNP 2
  • Green-Orange 2
  • Probe
  • ISH 7
APPLY FILTERS
REINITIALIZE


Cat#
Description
Cond.
Price Bef. VAT
Z-2033-200
 0,2ml/20tests 
Z-2033-50
 0,05ml/5tests 
C-3033-400
 0,4ml/40tests 
C-3033-100
 0,1ml/10tests 
EGFR-20-RE
 20Tests-40µl 
EGFR-20-GR
 20Tests-40µl 
EGFR-20-OR
 20Tests-40µl