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Anti-ITGA5 Polyclonal Antibody

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Cat# NB-64-113563-100uL

Size : 100uL

Brand : Neo Biotech


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Anti-ITGA5 Polyclonal Antibody

(Synonyms: VLA-5, ITGA5, Integrin α-F, Integrin α-5, Integrin Alpha-F, Integrin Alpha-5, FNRA, Fibronectin Receptor Subunit α, Fibronectin Receptor Subunit Alpha, CD49e, CD49 Antigen-Like Family Member E) Copy Product Info

Synonyms: VLA-5, ITGA5, Integrin α-F, Integrin α-5, Integrin Alpha-F, Integrin Alpha-5, FNRA, Fibronectin Receptor Subunit α, Fibronectin Receptor Subunit Alpha, CD49e, CD49 Antigen-Like Family Member E

Catalog No. TMAB-00991 Copy Product Info
Anti-ITGA5 Polyclonal Antibody is a Rabbit antibody targeting ITGA5. Anti-ITGA5 Polyclonal Antibody can be used in WB.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-ITGA5 Polyclonal Antibody is a Rabbit antibody targeting ITGA5. Anti-ITGA5 Polyclonal Antibody can be used in WB.
SynonymsVLA-5, ITGA5, Integrin α-F, Integrin α-5, Integrin Alpha-F, Integrin Alpha-5, FNRA, Fibronectin Receptor Subunit α, Fibronectin Receptor Subunit Alpha, CD49e, CD49 Antigen-Like Family Member E
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Sample:
Lane 1: NIH/3T3 (Mouse) Cell Lysate at 30 μg
Lane 2: A549 (Human) Cell Lysate at 30 μg
Lane 3: U87MG (Human) Cell Lysate at 30 μg
Lane 4: K562 (Human) Cell Lysate at 30 μg
Lane 5: Huvec (Human) Cell Lysate at 30 μg
Primary: Anti-Integrin alpha 5 (TMAB-00991) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 140 kDa
Observed band size: 140 kDa
Anti-ITGA5 Polyclonal Antibody
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Integrin alpha-5 light chain
Antigen Species
Human
Gene Name
ITGA5
Gene ID
3678
Protein Name
Integrin alpha-5
Uniprot ID
P08648
Biology Area
Transmembrane,Alpha,Endothelial Markers,Mast Cell Lineage
Function
CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late (activation) antigen 5 (VLA5); in platelets as glycoprotein IcIIa; and in fibroblasts as extracellular matrix receptor 6 (ECMVI). In addition to adhesion, integrins are known to participate in cell surface mediated signalling.
Chemical Properties
Molecular WeightTheoretical: 110 kDa. Actual: 140 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Keywords

VLA5VLA 5ITGA-5ITGA 5Integrin a-FIntegrin a-5
Related Tags: Anti-ITGA5 Polyclonal Antibody molecular weight