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> BDNF Protein, Rat, Recombinant (His)

BDNF Protein, Rat, Recombinant (His)

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Cat# NB-64-51920-1mg

Size : 1mg

Brand : Neo Biotech


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BDNF Protein, Rat, Recombinant (His)

(Synonyms: proBDNF, Neurotrophic factor BDNF precursor form, Brain-derived neurotrophic factor, Bdnf) Copy Product Info

Synonyms: proBDNF, Neurotrophic factor BDNF precursor form, Brain-derived neurotrophic factor, Bdnf

Catalog No. TMPH-03251 Copy Product Info
BDNF Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is P23363.
Other Forms of BDNF Protein, Rat, Recombinant (His):
BDNF Protein, Human/Murine/Rat, Recombinant
BDNF Protein, Mouse, Recombinant (His)
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
BDNF Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is P23363.
Species
Rat
Expression System
E. coli
TagN-6xHis
Accession NumberP23363
Amino AcidRRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTL
Construction136-243 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsproBDNF, Neurotrophic factor BDNF precursor form, Brain-derived neurotrophic factor, Bdnf
Research Background
Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.; Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse.
Chemical Properties
Molecular Weight16.3 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: BDNF Protein, Rat, Recombinant (His) chemical structure | BDNF Protein, Rat, Recombinant (His) molecular weight