PAR3 Polyclonal Antibody
Cat# bs-2921R
Size : 100uL
Brand : Bioss
Formalin-fixed and paraffin embedded human cervical cancer labeled with Anti-PAR3 Polyclonal Antibody, Unconjugated (bs-2921R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-2921R |
| Product Name | PAR3 Polyclonal Antibody |
| Applications | WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Cow, Pig, Chicken, Rabbit |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PARD-3 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 56288 |
| Swiss Prot | Q8TEW0 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | Baz; ASIP; PAR3; PARD-3; PARD3A; SE2-5T2; PPP1R118; SE2-5L16; SE2-5LT1; PAR3alpha; Partitioning defective 3 homolog; PAR-3; Atypical PKC isotype-specific-interacting protein; CTCL tumor antigen se2-5; PAR3-alpha; PARD3; PAR3A |
| Background | Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.<
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