Rab5a

Cat# 532369-100ul

Size : 100ul

Brand : US Biological



532369 Rab5a

Clone Type
Monoclonal
Host
mouse
Source
human
Swiss Prot
P20339
Isotype
IgG2b,k
Grade
Affinity Purified
Applications
E IC IF WB
Crossreactivity
Hu
Accession #
NP_004153
Shipping Temp
Blue Ice
Storage Temp
-20°C

Rab5a is a member of the RAS oncogene family. Rab5a is a small GTPase localized to the plasma membrane and early endosomes. It is a crucial regulatory component of the endocytic pathway. Activation of Rab5a is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex.

Applications:
Suitable for use in ELISA, Western Blot and Immunofluorescence/Immunocytochemistry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Mab|Isotype: IgG2b,k|Clone No: 3A4|Host: mouse|Source: human|Concentration: ~1mg/ml|Form: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.|Purity: Purified by Protein A affinity chromatography from tissue culture supernatant..|Immunogen: Recombinant protein corresponding to aa1-215 from human Rab5a expressed in E. coli.|Specificity: Recognizes human Rab5a.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Recombinant protein corresponding to aa1-215 from human Rab5a expressed in E. coli.
Form
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.
Purity
Purified by Protein A affinity chromatography from tissue culture supernatant..
Specificity
Recognizes human Rab5a.
References
1. Bucci C, et al., (1992) Cell 70 (5): 715-28, 2.|Seachrist JL, et al., (2002) J. Biol. Chem. 277 (1): 679-85|

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