Recombinant Human FSHB (C-6His)

Cat# CA13-50ug

Size : 50ug

Brand : Novoprotein


Description
Recombinant Human Follicle-Stimulating Hormone Subunit Beta is produced by our Mammalian expression system and the target gene encoding Asn19-Glu129 is expressed with a 6His tag at the C-terminus.
Accession
P01225
Known As
Follitropin Subunit Beta; Follicle-Stimulating Hormone Beta Subunit; FSH-B; FSH-Beta; Follitropin Beta Chain; FSHB
Mol Mass
13.5 KDa
APMol Mass
21 KDa, reducing conditions
Formulation Description
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Endotoxin
< 1 EU/µg as determined by LAL test.
Purity-SDS-PAGE
Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Reconstitution
  • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
  • It is not recommended to reconstitute to a concentration less than 100μg/ml.
  • Dissolve the lyophilized protein in distilled water.
  • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Shipping
  • The product is shipped at ambient temperature.
  • Upon receipt, store it immediately at the temperature listed below.
Storage
  • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
  • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
  • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Background
Follitropin Subunit β (FSHB) is a secreted protein that belongs to the glycoprotein hormones subunit β family. The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. FSHB exists in a heterodimer of a common α chain and an unique β chain that confers biological specificity to thyrotropin, lutropin, follitropin, and gonadotropin. FSHB stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD).