Rho A (26C4)
Cat# sc-418
Size : 200µg/ml
Brand : Santa Cruz Biotechnology
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Anticorps RhoA (26C4): sc-418
- L'anticorps RhoA 26C4 est un monoclonal IgG1 κ L'Anticorps RhoA, cité dans 1.281 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 120-150 de d'origine human
- L'Anticorps RhoA (26C4) est recommandé pour la détection de Rho A d'origine mouse, rat et human par WB, IP, IF, IHC(P) et FCM; également réactif avec d'autres espèces, dont et equine, bovine, porcine and canine
- Anti-L'Anticorps RhoA (26C4) est disponible conjugué à l'agarose pour IP; à l'HRP pour WB, IHC(P) et ELISA; et soit à la phycoerythrin ou FITC pour IF, IHC(P) et FCM
- aussi disponible conjugué à l'Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 ou Alexa Fluor® 647 pour WB (RGB), IF, IHC(P) et FCM
- aussi disponible conjugué à l'Alexa Fluor® 680 ou Alexa Fluor® 790 pour WB (NIR), IF et FCM
- aussi disponible conjugué à la biotine pour WB, IHC(P) et ELISA; et au TRITC pour IF, IHC(P) et FCM
- m-IgG Fc BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps RhoA (26C4) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps RhoA (26C4) ().
ACCÈS RAPIDE AUX LIENS
, Rho A, Rho B, Rho C, Rho D, Rho G, Rho GAP p190-B, Rho J, Rho T1 et Rho V
Rho A Antibody (26C4) is an IgG1 κ mouse monoclonal Rho A antibody (also designated RHOA antibody) that detects the Rho A protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM. Rho A Antibody (26C4) is available as both the non-conjugated anti-Rho A antibody form, as well as multiple conjugated forms of anti-Rho A antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
References:
- Post-translational modifications of p21rho proteins. | Adamson, P., et al. 1992. J Biol Chem. 267: 20033-8. PMID: 1400319
- Expression of the ras-related ralA, rho12 and rab genes in adult mouse tissues. | Olofsson, B., et al. 1988. Oncogene. 3: 231-4. PMID: 2457862
- Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins. | Garrett, MD., et al. 1989. J Biol Chem. 264: 10-3. PMID: 2491843
- Scrape-loading of Swiss 3T3 cells with ras protein rapidly activates protein kinase C in the absence of phosphoinositide hydrolysis. | Morris, JD., et al. 1989. Oncogene. 4: 27-31. PMID: 2536916
- The ras superfamily proteins. | Chardin, P. 1988. Biochimie. 70: 865-8. PMID: 3145021
- ras genes. | Barbacid, M. 1987. Annu Rev Biochem. 56: 779-827. PMID: 3304147
- Nucleotide sequence of human rho cDNA clone 12. | Yeramian, P., et al. 1987. Nucleic Acids Res. 15: 1869. PMID: 3822842
- A novel ras-related gene family. | Madaule, P. and Axel, R. 1985. Cell. 41: 31-40. PMID: 3888408
Espèces | Nom du Gène | Gene ID | Localisation chromosomique | Numéro d'accession de l'isoforme (ARNm) | Numéro d'accès aux protéines | Numéro OMIM™ |
---|---|---|---|---|---|---|
Human | RHOA | Entrez Gene ID: 387 | 3p21.31 | NM_001313941, NM_001313943, NM_001313944, NM_001313945, NM_001313946, NM_001313947, NM_001664 | UniProt ID: P61586 | 165390 |
Mouse | Rhoa | Entrez Gene ID: 11848 | 9 F2 | NM_001313961, NM_001313962, NM_016802 | UniProt ID: Q9QUI0 | N/A |
Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz® conjugates which eliminates the need for a secondary antibody.
Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-RhoA Antibody (26C4) has 1,281 citations in a variety of scientific publications.
Primary antibodies like Anti-RhoA Antibody (26C4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps RhoA (26C4) | sc-418 | 200 µg/ml | .00 | |||
RhoA (26C4): m-IgG Fc BP-HRP Kit | sc-528109 | 200 µg Ab; 10 µg BP | .00 | |||
RhoA (26C4): m-IgGκ BP-HRP Kit | sc-520407 | 200 µg Ab, 40 µg BP | .00 | |||
Anticorps RhoA (26C4) AC | sc-418 AC | 500 µg/ml, 25% agarose | .00 | |||
Anticorps RhoA (26C4) HRP | sc-418 HRP | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) FITC | sc-418 FITC | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) PE | sc-418 PE | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) Alexa Fluor® 488 | sc-418 AF488 | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) Alexa Fluor® 546 | sc-418 AF546 | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) Alexa Fluor® 594 | sc-418 AF594 | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) Alexa Fluor® 647 | sc-418 AF647 | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) Alexa Fluor® 680 | sc-418 AF680 | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) Alexa Fluor® 790 | sc-418 AF790 | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) B | sc-418 B | 200 µg/ml | .00 | |||
Anticorps RhoA (26C4) TRITC | sc-418 TRITC | 200 µg/ml | .00 |
Hi, is this antibody capable to distinguish the active RhoA (RhoA-GTP) and the inactive form?
Hi, what is the clone of rhoA antibody (sc-418)??
Hello, Could you tell me please if I can use Rho A Antibody (26C4): sc-418 with Opal 4-color IHC Kit (PerkinElmer), please? Secondly, is this antibody/sc-418 labelled/conjugates with any fluorophore? Many thanks. Kind regards, Sami
How can this mouse monoclonal antibody be used for immunohistochemical staining of mouse tissue?
What is the recommended secondary reagent for Western blot using this mouse monoclonal primary antibody?
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