BNUB3811-100 | SOX2 (Embryonic Stem Cell Marker)(SOX2/3811R), 0.2mg/mL

SOX2 Recombinant Monoclonal Rabbit Antibody (SOX2/3811R)

Add to Cart

This product is available by special order only.

Please fill in the inquiry form and we will contact you shortly.

Don't see what you're looking for? Contact us for more conjugation options.

Request Quote or Bulk Order

Formalin-fixed, paraffin-embedded human cervical carcinoma stained with SOX2 Recombinant Rabbit Monoclonal Antibody (SOX2/3811R).

View Spectra Viewer

Antibody Finder

Request Custom Conjugation

Product Description

SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the CF® Dye Brochure for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Stock status: Because Biotium offers a large number of antibody and conjugation options, primary antibody conjugates may be made to order. Typical lead times are up to one week for CF® dye and biotin conjugates, and up to 2-3 weeks for fluorescent protein and enzyme conjugates. Please email [email protected] to inquire about stock status and lead times before placing your order.

Catalog number key for antibody number 3811, Anti-SOX2 (SOX2/3811R)

Antibody # prefix	Conjugation	Ex/Em (nm)	Laser line	Detection channel	Dye Features
BNC04	CF®405S	404/431	405	DAPI (microscopy), AF405	CF®405S Features
BNC88	CF®488A	490/515	488	GFP, FITC	CF®488A Features
BNC68	CF®568	562/583	532, 561	RFP, TRITC	CF®568 Features
BNC94	CF®594	593/614	561	Texas Red®	CF®594 Features
BNC40	CF®640R	642/662	633-640	Cy®5	CF®640R Features
BNC47	CF®647	650/665	633-640	Cy®5	CF®647 Features
BNC74	CF®740	742/767	633-685	775/50	CF®740 Features
BNCB	Biotin	N/A	N/A	N/A
BNUB	Purified	N/A	N/A	N/A
BNUM	Purified, BSA-free	N/A	N/A	N/A

Alexa Fluor, Pacific Blue, Pacific Orange, and Texas Red are trademarks or registered trademarks of Thermo Fisher Scientific; Cy is a registered trademark of Cytiva; IRDye, LI-COR, and Odyssey are registered trademarks of LI-COR Bioscience.

Technology

CF® Dyes

Considerations for Immunofluorescence Staining

Primary & Secondary Antibody Conjugates

Product Attributes

Antibody number

#3811

Antibody reactivity (target)

SOX2

Antibody type

Primary

Host species

Rabbit

Clonality

Monoclonal, Recombinant Monoclonal

Clone

SOX2/3811R

Isotype

IgG, kappa

Molecular weight

34 kDa

Synonyms

ANOP3; Delta EF2a; MCOPS3 (Microphthalmia Syndromic type 3); SOX-2; SRY (sex determining region Y) box 2; SRY related HMG box 2; Transcription factor SOX-2; ysb

Human gene symbol

SOX2

Entrez gene ID

6657

SwissProt

P48431

Unigene

518438

Immunogen

Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)

Verified antibody applications

IHC (FFPE) (verified)

Antibody target cellular localization

Nucleus

Species reactivity

Human, Mouse

Positive control

MCF-7 cells. Lung or Cervical carcinoma.

Shipping condition

Room temperature

Storage Conditions

Store at 2 to 8 °C, Protect fluorescent conjugates from light, Note: store BSA-free antibodies at -10 to -35 °C

Regulatory status

For research use only (RUO)

Antibody/conjugate formulation

Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA, Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide

Shelf life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Product origin

Product may contain either bovine serum albumin (BSA) from bovine serum (Bos taurus), or recombinant BSA produced in Chinese hamster ovary cells. Inquire for the specific lot.

Cell/tissue expression

Stem cells

Tumor expression

Melanoma

Documents, Protocols, SDS and COA

Datasheet

Datasheet Download

COA

Request the Certificate of Analysis

SOX2 (Embryonic Stem Cell Marker)(SOX2/3811R), 0.2mg/mL

Cat# BNUB3811-100

Brand : Biotium