Ion exchange (IEX) FPLC columns
Ion exchange chromatography (IEX) resins are commonly used to separate molecules, such as large proteins, small nucleotides, and amino acids, depending on their charge. The functional groups in the IEX resins have charges that bind the molecules with opposite charges. The release of the molecules bound to the resin is carried out by charge displacement, via the application of an increasing concentration of a molecule of the same charge.
Depending on the size of the beads, the pore size, the functional groups and the mechanical strength of the individual base matrices, our IEX resins can be used to capture bulk products or impurities from large volumes , as an intermediate step or as a final step for high resolution purifications.
We offer a wide range of ion exchange chromatography media (resins). Depending on the nature of your application, the property of your raw material and the resolution you need, you will find the right resin for you.
There are different types of exchangers:
- Strong exchangers: Q, S, SP. These exchangers make it possible to work on a wide pH range.
- Weak exchangers: DEAE, ANX, CM. It is advisable to use these exchangers if the selectivity of the strong ion exchangers is not satisfactory. However, the ion exchange capacity of a weak ion exchanger varies with pH.
- Multimodal ligands (MMC) provide ionic interaction, hydrogen bonding and hydrophobic interaction. The MMC behaves like a weak cation exchanger, but allows a high conductivity bond.
Frequently Asked Questions (FAQ)
Where can I find ion exchange (iex) products on the CliniSciences website?
ion exchange (iex) products are available in this section and can be sorted by product families or sub-categories, such as Positively charged proteins, Negatively charged proteins. You can browse the catalogue tree or use the search bar with a product name, catalogue reference, brand or supplier.
What types of products are available in the ion exchange (iex) category?
The ion exchange (iex) category brings together various product references, consumables, reagents, kits, instruments or laboratory solutions, depending on the relevant product family. The Negatively charged proteins, Positively charged proteins sub-categories allow you to find the products that meet your needs more quickly.
How can I quickly find a ion exchange (iex) product?
To find a ion exchange (iex) product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.
Does CliniSciences stock several product codes in the ion exchange (iex) category?
Yes, CliniSciences distributes several product references in the ion exchange (iex) category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.
Can I request a quote for ion exchange (iex) products?
Yes, you can request a quote for ion exchange (iex) products from the product page or by contacting CliniSciences (info@clinisciences.com). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.
How can I find out if a ion exchange (iex) product is available to order?
The availability of a ion exchange (iex) product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact CliniSciences with the product code or name of the product you are looking for.
What should I do if I cannot find the ion exchange (iex) product I am looking for?
If the ion exchange (iex) product you are looking for does not appear in the catalogue, please contact CliniSciences with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.
Are all ion exchange (iex) products available under the same terms and conditions?
No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.