General Info
| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Protein GPR15LG (19-69 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | GPR15LG |
| Gene ID: | 387695 |
| Uniprot ID: | GP15L_HUMAN |
| Immunogen Region: | 19-69 aa |
| Specificity: | This antibody detects endogenous levels of CJ099 at Human |
| Immunogen: | Synthesized peptide derived from the human CJ099 at the amino acid range 19-69 |
Description
| Function | Highly cationic protein that has multiple functions. Acts as a chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor.together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May regulate keratinocyte proliferation. In addition, through activation of Mas-related G protein-coupled receptors (MRGPRs) contributes to pruritogenesis by activating itch-selective sensory neurons and mast cells degranulation. Has antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Actinomyces spec., and Mycoplasma hominis and lentivirus. |
| Protein Name | Protein Gpr15lgAntimicrobial Peptide With 57 Amino Acid ResiduesAp-57Antimicrobial Peptide-57Colon-Derived Susd2 Binding FactorCsbfProtein Gpr15 LigandProtein Gpr15lSecreted Protein C10orf99 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Protein Gpr15lg antibodyAnti-Antimicrobial Peptide With 57 Amino Acid Residues antibodyAnti-Ap-57 antibodyAnti-Antimicrobial Peptide-57 antibodyAnti-Colon-Derived Susd2 Binding Factor antibodyAnti-Csbf antibodyAnti-Protein Gpr15 Ligand antibodyAnti-Protein Gpr15l antibodyAnti-Secreted Protein C10orf99 antibodyAnti-GPR15LG antibodyAnti-C10orf99 antibodyAnti-GPR15L antibodyAnti-UNQ1833 antibodyAnti-PRO3446 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance