General Info
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-SNTB2 (200-300) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | SNTB2 |
| Gene ID: | 6645 |
| Uniprot ID: | SNTB2_HUMAN |
| Immunogen Region: | 200-300 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SNTB2 (NP_006741.1). |
| Immunogen Sequence: | VTPYIKKPSLVSDLPWEGAA PQSPSFSGSEDSGSPKHQNS TKDRKIIPLKMCFAARNLSM PDLENRLIELHSPDSRNTLI LRCKDTATAHSWFVAIHTNI M |
Description
| Tissue Specificity | Ubiquitous. Isoform 1 is the predominant isoform. Weak level of isoform 2 is present in all tested tissues, except in liver and heart where it is highly expressed. |
| Post Translational Modifications | Phosphorylated. Partially dephosphorylated upon insulin stimulation. |
| Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN. |
| Protein Name | Beta-2-Syntrophin59 Kda Dystrophin-Associated Protein A1 Basic Component 2Syntrophin-3Snt3Syntrophin-LikeSntl |
| Cellular Localisation | MembraneCytoplasmic VesicleSecretory Vesicle MembranePeripheral Membrane ProteinCell JunctionCytoplasmCytoskeletonMembrane-AssociatedIn MuscleIt Is Exclusively Localized At The Neuromuscular JunctionIn Insulinoma Cell LineIt Is Enriched In Secretory Granules |
| Alternative Antibody Names | Anti-Beta-2-Syntrophin antibodyAnti-59 Kda Dystrophin-Associated Protein A1 Basic Component 2 antibodyAnti-Syntrophin-3 antibodyAnti-Snt3 antibodyAnti-Syntrophin-Like antibodyAnti-Sntl antibodyAnti-SNTB2 antibodyAnti-D16S2531E antibodyAnti-SNT2B2 antibodyAnti-SNTL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance