General Info
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-UGGT1 (1456-1555) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | UGGT1 |
| Gene ID: | 56886 |
| Uniprot ID: | UGGG1_HUMAN |
| Immunogen Region: | 1456-1555 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1456-1555 of human UGGT1 (NP_064505.1). |
| Immunogen Sequence: | PNNMIHQVPIKSLPQEWLWC ETWCDDASKKRAKTIDLCNN PMTKEPKLEAAVRIVPEWQD YDQEIKQLQIRFQKEKETGA LYKEKTKEPSREGPQKREEL |
Description
| Tissue Specificity | Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart. |
| Function | Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. |
| Protein Name | Udp-Glucose -Glycoprotein Glucosyltransferase 1Ugt1Hugt1Udp--Glc -Glycoprotein GlucosyltransferaseUdp-Glucose Ceramide Glucosyltransferase-Like 1 |
| Database Links | Reactome: R-HSA-901032 |
| Cellular Localisation | Endoplasmic Reticulum LumenEndoplasmic Reticulum-Golgi Intermediate Compartment |
| Alternative Antibody Names | Anti-Udp-Glucose -Glycoprotein Glucosyltransferase 1 antibodyAnti-Ugt1 antibodyAnti-Hugt1 antibodyAnti-Udp--Glc -Glycoprotein Glucosyltransferase antibodyAnti-Udp-Glucose Ceramide Glucosyltransferase-Like 1 antibodyAnti-UGGT1 antibodyAnti-GT antibodyAnti-UGCGL1 antibodyAnti-UGGT antibodyAnti-UGT1 antibodyAnti-UGTR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance