Anti-Zebrafish NEDD8/8l Antibody

Product Name

Anti-Zebrafish NEDD8/8l Antibody

View all NEDD8/8l Antibodies

SKU/Catalog Number

AZF1QMF9

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Zebrafish NEDD8/8l Antibody catalog #AZF1QMF9. Tested in IHC applications. This antibody reacts with Zebrafish.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-Zebrafish NEDD8/8l Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # AZF1QMF9)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Immunogen

E.coli-derived zebrafish NEDD8/8l recombinant protein (Position: M1-G76)

Reactive Species

AZF1QMF9 is reactive to NEDD8/8l in Zebrafish

Background of NEDD8/8l

NEDD8 is a protein that in humans is encoded by the NEDD8 gene. Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The most substrates of NEDD8 modification are the Cullin subunits of Cullin-based E3 ubiquitin ligases, which are active only when neddylated. Their NEDDylation is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation. NEDD8 modification has therefore been implicated in cell cycle progression and cytoskeletal regulation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details