Specifications

Product Data
Applications	IHC
Recommended Dilution	IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivities	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	Synthetic peptide of human BSN
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Gene Name	bassoon presynaptic cytomatrix protein
Database Link	NP_003449 Entrez Gene 12217 MouseEntrez Gene 29138 RatEntrez Gene 8927 Human UniProt ID Q9UPA5
Background	Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses.
Synonyms	ZNF231
Reference Data