CD56 (Neural Cell Adhesion Molecule, NCAM) (AP)

Cat# MBS6122177-0,1mL

Size : 0.1mL

Brand : MyBiosource

CD56 (Neural Cell Adhesion Molecule, NCAM) (AP)

CD56 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6122177

MBS6122177 is an antibody targeting CD56. Also known as CD56 (Neural Cell Adhesion Molecule, NCAM) (AP). Reactive in Human, Rat, Zebrafish. Host: Mouse. More details

Product Overview

Online Datasheet in PDF
Product Name
CD56, Monoclonal Antibody
Full Product Name
CD56 (Neural Cell Adhesion Molecule, NCAM) (AP)
Product Gene Name
anti-CD56 antibody
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
123C3.D5
Host
Mouse
Species Reactivity
Human, Rat, Zebrafish
Form/Format
Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein G Affinity Chromatography
Specificity
Recognizes human CD56. Species Crossreactivity: rat and zebrafish. Recognizes two proteins (185kD & 145kD), identified as two isoforms of neural cell adhesion molecule (NCAM/CD56).
Preparation and Storage
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing alkaline phosphatase conjugates will result in a substantial loss of activity.
Molecular Weight
40,760 Da
OMIM
116930
3D Structure
ModBase 3D Structure for P13591
Immunogen
Membrane preparation of a small cell lung carcinoma
Conjugate
AP
Positive Control
Cerebellum, Pancreas, Neuroblastoma

Product Categories/Family for anti-CD56 antibody

Antibodies; CD Markers
Applications Tested/Suitable for anti-CD56 antibody
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-CD56 antibody
IP: 1-2ug/500ug protein lysate
IF: 1-2ug/ml
WB: 0.5-1ug/ml
Applications are based on unconjugated antibody.

Immunohistochemistry (IHC) of anti-CD56 antibody

Formalin-fixed, paraffin-embedded human colon ganglion cells stained with CD56 antibody at 1:100 using peroxidase-conjugate and DAB chromogen. Staining of formalin/paraffin tissues REQUIRES boiling tissue sections in 10mM citrate buffer, pH 6.0.
Mouse Anti-CD56 Monoclonal Antibody – Cat# MBS6122177

Product References and Citations for anti-CD56 antibody

1. Gerardy-Schahn R; et. al. Int Journal of Cancer. Supplement, 1994, 8:38-42. 2. Michalides R; et. al. International Journal of Cancer. Supplement, 1994, 8:34-7. 3. Schol DJ; et. al. Int J Cancer. Supplement, 1988, 2:34-40.

Other Notes

Small volumes of anti-CD56 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD56. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neural cell adhesion molecule 1 isoform 1
NCBI Official Synonym Full Names
neural cell adhesion molecule 1
NCBI Official Symbol
NCAM1
NCBI Official Synonym Symbols
CD56; NCAM; MSK39
UniProt Protein Name
Neural cell adhesion molecule 1
UniProt Synonym Protein Names
CD_antigen: CD56
UniProt Gene Name
NCAM1
UniProt Synonym Gene Names
NCAM; N-CAM-1; NCAM-1
UniProt Entry Name
NCAM1_HUMAN
NCBI Protein Information
neural cell adhesion molecule 1; antigen recognized by monoclonal antibody 5.1H11; neural cell adhesion molecule, NCAM

UniProt Comments for CD56

NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11q23.1

Cellular Component: Golgi membrane; cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: identical protein binding

Biological Process: axon guidance; extracellular matrix organization and biogenesis; cytokine and chemokine mediated signaling pathway; cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD56 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 ECM Proteoglycans Pathway antibodies  ECM Proteoglycans Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram

Diseases associated with anti-CD56 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >984 publications with CD56 and Nervous System Diseases
 Brain Diseases Antibodies  >537 publications with CD56 and Brain Diseases
 Necrosis Antibodies  >276 publications with CD56 and Necrosis
 Disease Models, Animal Antibodies  >257 publications with CD56 and Disease Models, Animal
 Inflammation Antibodies  >237 publications with CD56 and Inflammation
 Lung Neoplasms Antibodies  >224 publications with CD56 and Lung Neoplasms
 Cardiovascular Diseases Antibodies  >219 publications with CD56 and Cardiovascular Diseases
 Congenital Abnormalities Antibodies  >195 publications with CD56 and Congenital Abnormalities
 Liver Diseases Antibodies  >179 publications with CD56 and Liver Diseases
 Neoplasm Invasiveness Antibodies  >146 publications with CD56 and Neoplasm Invasiveness

Organs/Tissues associated with anti-CD56 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2715 publications with CD56 and Brain
 Blood Antibodies  >2492 publications with CD56 and Blood
 Nerve Antibodies  >1729 publications with CD56 and Nerve
 Embryonic Tissue Antibodies  >831 publications with CD56 and Embryonic Tissue
 Muscle Antibodies  >564 publications with CD56 and Muscle
 Bone Antibodies  >525 publications with CD56 and Bone
 Skin Antibodies  >379 publications with CD56 and Skin
 Vascular Antibodies  >365 publications with CD56 and Vascular
 Eye Antibodies  >337 publications with CD56 and Eye
 Lung Antibodies  >326 publications with CD56 and Lung