ALS13186 | CSF1 / MCSF Antibody (clone 2D10) Clinisciences

Product Information
Application Applications Legend: WB=Western Blot IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin-embedded Sections) IHC-F=Immunohistochemistry (Frozen Sections) IF=Immunofluorescence FC=Flow Cytopmetry IC=Immunochemistry ICC=Immunocytochemistry E=ELISA IP=Immunoprecipitation DB=Dot Blot CHIP=Chromatin Immunoprecipitation FA=Fluorescence Assay IEM=Immunoelectronmicroscopy EIA=Enzyme Immunoassay	WB, IHC-P, E
Primary Accession	P09603
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Clone Names	2D10
Calculated MW	60kDa
Dilution	IHC-P (1:200), WB (1:500-1:2000),

Additional Information
Gene ID	1435
Other Names	Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, Lanimostim, Processed macrophage colony-stimulating factor 1, CSF1
Target/Specificity	Human CSF1
Reconstitution & Storage	Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
Precautions	CSF1 / MCSF Antibody (clone 2D10) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	CSF1
Function	Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Cellular Location	Cell membrane; Single-pass type I membrane protein
Volume	50 µl

CSF1 / MCSF Antibody (clone 2D10)