| Short Description : | This PVRL4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 52pg/mL |
| Detection Limit: | 125-8000pg/mL |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
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| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. |
| Post Translational Modifications | The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE. |
| Function | Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus. |
| Protein Name | Nectin-4Ig Superfamily Receptor LnirNectin Cell Adhesion Molecule 4Poliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionAdherens JunctionColocalizes With Afdn At Cadherin-Based Adherens JunctionsProcessed Poliovirus Receptor-Related Protein 4: SecretedThe Secreted Form Is Found In Breast Tumor Patients |
| Alternative ELISA Names | Nectin-4 ELISA kitIg Superfamily Receptor Lnir ELISA kitNectin Cell Adhesion Molecule 4 ELISA kitPoliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4 ELISA kitNECTIN4 ELISA kitLNIR ELISA kitPRR4 ELISA kitPVRL4 ELISA kit |
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Information sourced from Uniprot.org

