Influenza A virus-IN-8

Cat# NB-64-79964-50mg

Size : 50mg

Brand : Neo Biotech


Influenza A virus-IN-8

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Influenza A virus-IN-8 (S5), a macrocyclic peptide, exhibits no cytotoxicity and acts as a potent inhibitor of Influenza A Virus (IAV), demonstrating significant protease stability, with IC50 values of 6.7 nM for H1 and 6.6 nM for H5 variants. It has a high affinity for H1 variants, binding to a conserved region in the HA stem with a dissociation constant (Kd) of 1.0 nM [1].

Influenza A virus-IN-8

Product Introduction

Bioactivity
Description
Influenza A virus-IN-8 (S5), a macrocyclic peptide, exhibits no cytotoxicity and acts as a potent inhibitor of Influenza A Virus (IAV), demonstrating significant protease stability, with IC50 values of 6.7 nM for H1 and 6.6 nM for H5 variants. It has a high affinity for H1 variants, binding to a conserved region in the HA stem with a dissociation constant (Kd) of 1.0 nM [1].
Chemical Properties
Molecular Weight2200.48
FormulaC104H142N28O24S
SequenceAc(1)-Tyr-Val-Leu-Phe-Arg-Trp-Asp-His-Gly-Thr-Leu-Ala-Thr-His-Trp-Val-Cys(1)-Gly-NH2
Sequence ShortYVLFRWDHGTLATHWVXG
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.