Reagents and instruments for immunology, cell biology and molecular biology.
 
> LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc)

LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc)

Print Print
Please log in

Cat# NB-64-54802-200ug

Size : 200ug

Brand : Neo Biotech


Remove All

LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc)

(Synonyms: MIR10, LIR2, LILRB2, ILT4CD85d, ILT-4, ILT4, CD85d) Copy Product Info

Synonyms: MIR10, LIR2, LILRB2, ILT4CD85d, ILT-4, ILT4, CD85d

Catalog No. TMPK-01100 Copy Product Info
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 74.1 kDa and the accession number is Q8N423-1.
Other Forms of LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc):
LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated
LILRB2/CD85d/ILT4 Protein, Human, Recombinant (His & Avi)
LILRB2/CD85d/ILT4 Protein, Human, Recombinant (His & Avi), Biotinylated
LILRB2/CD85d/ILT4 Domain1 & 2 Protein, Human, Recombinant (His)
LILRB2/CD85d/ILT4 Protein, Human, Recombinant (mFc)
LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recombinant (hFc)
LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recombinant (His)
IL-T4 Protein, Human, Recombinant (His)
IL-T4 Protein, Human, Recombinant (hFc)
IL-T4 Protein, Human, Recombinant (His & Avi), Biotinylated
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Bioactivity
1. Immobilized Human LILRB2, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-LILRB2 Antibody, hFc Tag with the EC50 of 14.6ng/ml determined by ELISA (QC Test). 2. Human LILRB2, hFc Tag captured on Protein A chip, can bind Human ANGPTL2, His Tag with an affinity constant of 0.14μM as determined in a SPR assay.
Description
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 74.1 kDa and the accession number is Q8N423-1.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberQ8N423-1
ConstructionGln22-His458
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsMIR10, LIR2, LILRB2, ILT4CD85d, ILT-4, ILT4, CD85d
Research Background
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles.
Chemical Properties
Molecular Weight74.1 kDa (predicted). Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Calculator

  • Reconstitution Calculator
  • Recombinant Protein Dilution Calculator
  • Specific Activity Calculator

Dose Conversion

Keywords

MIR-10MIR 10LIR-2LIR 2LILRB-2LILRB 2ILT 4
Related Tags: LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc) chemical structure | LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc) molecular weight