Maltodextrin, dextrose equivalent 5.0-8.0 [9050-36-6]
Cat# HY-W250795B-100g
Size : 100g
Brand : MedChemExpress
| Description |
Maltodextrin, dextrose equivalent 5.0-8.0 can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1]. |
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| In Vitro |
Maltodextrin, dextrose equivalent 5.0-8.0 is a polysaccharide with good biocompatibility and drug encapsulation ability, that encapsulates BSA as a model protein with an efficiency of about 70% and a loading rate of up to 20%. Maltodextrin, dextrose equivalent 5.0-8.0 exhibits non-toxic to cells at a concentrations of 5 mg/mL, and can be used in drug delivery system. The glucose equivalent (DE) value reflects the degree of hydrolysis of maltodextrin. The higher the DE value, the higher the degree of hydrolysis is. Maltodextrin, dextrose equivalent 5.0-8.0 forms stable nanoparticles with particle sizes ranging from 170 nm to 450 nm and a narrow particle size distribution[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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| Formula |
(C6H10O5)n·xH2O |
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| CAS No. | |||||||
| Appearance |
Solid |
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| Color |
White to off-white |
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| SMILES |
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@H]2[C@@H](COC)O[C@H](O16)[C@H](O)[C@H]2O)O1.26.[x] |
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| Shipping | Room temperature in continental US; may vary elsewhere. |
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| Storage |
Store at room temperature, keep dry and cool
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| Solvent & Solubility |
In Vitro:
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
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| Purity & Documentation | |||||||
| References |