Mouse CAPN1 (Calpain 1, Large Subunit) Sandwich ELISA Kit

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Capn1
Gene ID:	12333
Uniprot ID:	CAN1_MOUSE
Sample Type:	tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Undergoes calcium-induced successive autoproteolytic cleavages that generate a membrane-bound 78 kDa active form and an intracellular 75 kDa active form. Calpastatin reduces with high efficiency the transition from 78 kDa to 75 kDa calpain forms.
Function	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-388' and 'His-410'. Cleaves and activates caspase-7 (CASP7).
Protein Name	Calpain-1 Catalytic Subunit Calcium-Activated Neutral Proteinase 1 Canp 1 Calpain Mu-Type Calpain-1 Large Subunit Micromolar-Calpain Mucanp
Database Links	Reactome: R-MMU-1474228 Reactome: -MMU-6798695
Cellular Localisation	Cytoplasm Cell Membrane Translocates To The Plasma Membrane Upon Ca(2+) Binding
Alternative ELISA Names	Calpain-1 Catalytic Subunit ELISA kit Calcium-Activated Neutral Proteinase 1 ELISA kit Canp 1 ELISA kit Calpain Mu-Type ELISA kit Calpain-1 Large Subunit ELISA kit Micromolar-Calpain ELISA kit Mucanp ELISA kit Capn1 ELISA kit Canp1 ELISA kit Capa1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance