Mouse EDN1 (Endothelin 1) Competitive ELISA Kit Ready-To-Use E0014951)

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	2.5 hrs

Gene Symbol:	Edn1
Gene ID:	13614
Uniprot ID:	EDN1_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity	Highest expression in the adult is in lung. Lower levels found in heart, kidney, brain and intestine. In the embryo, expressed in outer and inner pharyngeal arch surfaces. Also expressed in endothelium of dorsal aorta and arch arteries, and in epithelium of pharyngeal pouches.
Post Translational Modifications
Function	Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. Also binds the DEAR/FBXW7-AS1 receptor.
Protein Name	Endothelin-1 Et-1 Preproendothelin-1 Ppet1 Cleaved Into - Big Endothelin-1
Database Links	Reactome: R-MMU-375276 Reactome: -MMU-416476
Cellular Localisation	Secreted
Alternative ELISA Names	Endothelin-1 ELISA kit Et-1 ELISA kit Preproendothelin-1 ELISA kit Ppet1 Cleaved Into - Big Endothelin-1 ELISA kit Edn1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance