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> OCT4 (1-265, His-Tag) Human Protein

OCT4 (1-265, His-Tag) Human Protein

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Cat# AR50772PU-N

Size : 500ug


OCT4 (1-265, His-Tag) Human Protein

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SKU
AR50772PU-N
Recombinant human Oct-3/4 protein
 

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Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MGSSHHHHHH SSGLVPRGSH MHFYRLFLGA TRRFLNPEWK GEIDNWCVYV LTSLLPFKIQ SQDIKALQKE LEQFAKLLKQ KRITLGYTQA DVGLTLGVLF GKVFSQTTIC RFEALQLSFK NMCKLRPLLQ KWVEEADNNE NLQEICKAET LVQARKRKRT SIENRVRGNL ENLFLQCPKP TLQQISHIAQ QLGLEKDVVR VWFCNRRQKG KRSSSDYAQR EDFEAAGSPF SGGPVSFPLA PGPHFGTPGY GSPHFTALYS SVPFPEGEAF PPVSVTTLGS PMHSN
Tag His-Tag
Predicted MW 32.2 kDa (285aa)
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 85% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE,Denatured
Protein Description Recombinant human OCT4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_001272916
Locus ID 5460
UniProt ID Q01860
Cytogenetics 6p21.33
Synonyms POU domain, class 5, transcription factor 1 isoform 3, Oct-3, Oct-4, OCT3, OCT4, OTF-3, OTF3, OTF4
Summary This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. provided by RefSeq, Oct 2013
Protein Categories ADC Targets, Cytokines, Intracellular Proteins, Transciption Factors
Protein Families Adult stem cells, Cancer stem cells, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors
FAQs
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SDS
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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