Recombinant Human Tissue Specific Transplantation Antigen P35B
Cat# MBS144067-5x1mg
Size : 5x1mg
Brand : MyBiosource
Tissue Specific Transplantation Antigen P35B (TSTA3) Human Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144067Description: TSTA3 Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 341 amino acids (1-321 a.a.) and having a molecular mass of 38 kDa. The TSTA3 is fused to 20 amino acid His-Tag at N-terminus and purified by… More details
Product Overview
Online Datasheet in PDFProduct Name
Tissue Specific Transplantation Antigen P35B (TSTA3), Recombinant Protein
Full Product Name
Recombinant Human Tissue Specific Transplantation Antigen P35B
Product Gene Name
TSTA3 recombinant protein
Product Synonym Names
TSTA3 Human; Tissue Specific Transplantation Antigen P35B Human Recombinant; FX; P35B; SDR4E1; GDP-L-fucose synthase; Protein FX
Sequence
MGSSHHH HHH SSGLVPRGSH MGEPQG SMRI LVTGGSGLVG KAIQKVVADG AGLPGEDWVF VSSKDADLTD TAQTRALFEK VQPTHVIHLA AMVGGLFRNI KYNLDFWRKN VHMNDNVLHS AFEVGARKVV SCLSTCIFPD KTTYPIDETM IHNGPPHNSN FGYSYAKRMI DVQNRAYFQQ YGCTFTAVIP TNVFGPHDNF NIEDGHVLPG LIHKVHLAKS SGSALTVWGT GNPRRQFIYS LDLAQLFIWV LREYNEVEPI ILSVGEEDEV SIKEAAEAVV EAMDFHGEVT FDTTKSDGQF KKTASNSKLR TYLPDFRFTP FKQAVKETCA WFTDNYEQAR K.
Host
E Coli
Form/Format
0.5mg/ml solution containing 20mM Tris pH-8, 2mM DTT, 50mM NaCl & 10% glycerol.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
TSTA3 Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
Other Notes
Small volumes of TSTA3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for TSTA3 purchase
MBS144067 is a recombinant protein targeting TSTA3. Also known as Recombinant Human Tissue Specific Transplantation Antigen P35B. Host: E Coli.
Additional Details
NCBI/Uniprot data below describe general gene information for TSTA3. It may not necessarily be applicable to this product.
NCBI Official Full Name
GDP-L-fucose synthase
NCBI Official Synonym Full Names
tissue specific transplantation antigen P35B
NCBI Official Symbol
TSTA3
NCBI Official Synonym Symbols
FX; P35B; SDR4E1
UniProt Protein Name
GDP-L-fucose synthase
UniProt Synonym Protein Names
GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; Protein FX; Red cell NADP(H)-binding protein; Short-chain dehydrogenase/reductase family 4E member 1
UniProt Gene Name
TSTA3
UniProt Synonym Gene Names
SDR4E1
UniProt Entry Name
FCL_HUMAN
NCBI Protein Information
GDP-L-fucose synthase; 3-5 epimerase/4-reductase; GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; red cell NADP(H)-binding protein; short chain dehydrogenase/reductase family 4E, member 1; tissue specific transplantation antigen 3
NCBI Summary for TSTA3
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for TSTA3
TSTA3: Two step NADP-dependent conversion of GDP-4-dehydro-6- deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the fucose synthase family.
Protein type: Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.271; Oxidoreductase; Carbohydrate Metabolism - amino sugar and nucleotide sugar
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: cytoplasm
Molecular Function: GDP-L-fucose synthase activity; electron carrier activity; isomerase activity; coenzyme binding; GDP-4-dehydro-D-rhamnose reductase activity
Biological Process: leukocyte adhesion; cytolysis; GDP-mannose metabolic process; 'de novo' GDP-L-fucose biosynthetic process
Show more Protein type: Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.271; Oxidoreductase; Carbohydrate Metabolism - amino sugar and nucleotide sugar
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: cytoplasm
Molecular Function: GDP-L-fucose synthase activity; electron carrier activity; isomerase activity; coenzyme binding; GDP-4-dehydro-D-rhamnose reductase activity
Biological Process: leukocyte adhesion; cytolysis; GDP-mannose metabolic process; 'de novo' GDP-L-fucose biosynthetic process
Research Articles on TSTA3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with TSTA3 recombinant protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies | Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram |
| Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies | Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram |
| Fructose And Mannose Metabolism Pathway antibodies | Fructose And Mannose Metabolism Pathway Diagram |
| Fructose And Mannose Metabolism Pathway antibodies | Fructose And Mannose Metabolism Pathway Diagram |
| GDP-L-fucose Biosynthesis I (from GDP-D-mannose) Pathway antibodies | GDP-L-fucose Biosynthesis I (from GDP-D-mannose) Pathway Diagram |
| Metabolic Pathways antibodies | Metabolic Pathways Diagram |
Diseases associated with TSTA3 recombinant protein
| Disease Name | Pubmed Publications |
|---|---|
| Carcinoma, Hepatocellular Antibodies | >3 publications with TSTA3 and Carcinoma, Hepatocellular |
| Liver Diseases Antibodies | >3 publications with TSTA3 and Liver Diseases |
| Anemia Antibodies | >2 publications with TSTA3 and Anemia |
| Adenocarcinoma Antibodies | >2 publications with TSTA3 and Adenocarcinoma |
| Hepatitis Antibodies | >2 publications with TSTA3 and Hepatitis |
| Liver Cirrhosis Antibodies | >1 publications with TSTA3 and Liver Cirrhosis |
| Nervous System Diseases Antibodies | >1 publications with TSTA3 and Nervous System Diseases |
| Breast Neoplasms Antibodies | >1 publications with TSTA3 and Breast Neoplasms |
| Fibrosis Antibodies | >1 publications with TSTA3 and Fibrosis |
| Inflammation Antibodies | >1 publications with TSTA3 and Inflammation |
Organs/Tissues associated with TSTA3 recombinant protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >6 publications with TSTA3 and Blood |
| Liver Antibodies | >2 publications with TSTA3 and Liver |
| Parathyroid Antibodies | >1 publications with TSTA3 and Parathyroid |
| Eye Antibodies | >1 publications with TSTA3 and Eye |
| Lung Antibodies | >1 publications with TSTA3 and Lung |