VEGF (Vascular Endothelial Growth Factor)(VG1), 0.2mg/mL

This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet-derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

Primary antibodies are available purified, or with a selection of fluorescent CF^® dyes and other labels. CF^® dyes offer exceptional brightness and photostability. See the CF^® Dye Brochure for more information. Note: Conjugates of blue fluorescent dyes like CF^®405S and CF^®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

 Catalog number key for antibody number 1686, Anti-VEGF (VG1)