VEGFR2/KDR Protein, Human, Recombinant (hFc)
Cat# NB-64-56215-1mg
Size : 1mg
Brand : Neo Biotech
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VEGFR2/KDR Protein, Human, Recombinant (hFc)
(Synonyms: VEGFR2, VEGFR, kinase insert domain receptor, Flk-1, FLK1, CD309) Copy Product InfoSynonyms: VEGFR2, VEGFR, kinase insert domain receptor, Flk-1, FLK1, CD309
Catalog No. TMPY-01044 Copy Product Info
VEGFR2/KDR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 109 kDa and the accession number is P35968-1.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human VEGF165, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human VEGF R2, hFc Tag with the EC50 of 7.8 ng/ml determined by ELISA (QC Test). Immobilized Human VEGF R2, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-VEGF R2 Antibody, hFc Tag with the EC50 of 9.7 ng/ml determined by ELISA. Loaded Human VEGF165, His-Avi Tag on Anti-His-Biosensor can bind Human VEGF R2, hFc Tag with an affinity constant of 2.34 nM as determined in BLI assay . |
| Description | VEGFR2/KDR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 109 kDa and the accession number is P35968-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc (IgG1) |
| Accession Number | P35968-1 |
| Construction | Ala20-Glu764 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | VEGFR2, VEGFR, kinase insert domain receptor, Flk-1, FLK1, CD309 |
| Research Background | The vascular endothelial growth factor receptor-2 (VEGFR-2/KDR/flk-1) functions as the primary mediator of vascular endothelial growth factor activation in endothelial cells. Regulation of VEGFR-2 expression appears critical in mitogenesis, differentiation, and angiogenesis. Transcriptional regulation of the VEGFR-2 is complex and may involve multiple putative upstream regulatory elements including E boxes. |
| Molecular Weight | 109 kDa (predicted); 150-180 kDa (reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Keywords
VEGFR-2VEGFR 2FLK 1CD-309CD 309
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Related Tags: VEGFR2/KDR Protein, Human, Recombinant (hFc) chemical structure | VEGFR2/KDR Protein, Human, Recombinant (hFc) molecular weight
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