Explore Dual-Target Immunotherapy Research: 25% OFF Murine Bispecific Antibodies

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Recombinant Murine Bispecific Antibodies for Immuno-Oncology Research

Two targets within a single antibody: ichorbio recombinant murine bispecific antibodies provide tools for investigating interconnected immune pathways and interactions between immune cells and target cells.

Designed for mouse research, the range supports studies of T-cell redirection, immune checkpoint modulation and the tumor microenvironment, combining two antigen-binding specificities within a single IgG molecule.

From 22 October to 31 December 2026, benefit from 25% off all ichorbio recombinant murine bispecific antibodies. No minimum order and no additional conditions: simply quote Q4BISPEC25 on your purchase order.

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Applications and Key Features

Research Applications

  • T-cell engagement and redirection
  • Immune checkpoint research
  • Co-stimulatory pathway investigation
  • Tumor microenvironment studies
  • Preclinical immuno-oncology

Key Features

  • Recombinant murine IgG formats
  • Two antigen-binding specificities in one molecule
  • LALAPG Fc engineering to reduce Fc-mediated effector interactions
  • Supplier-reported purity >95%
  • Supplier-reported endotoxin <1 EU/mg
  • Carrier- and preservative-free formulations

Experimental Considerations

Select a target pair according to antigen expression, the biological question and your mouse model.

Check the reference-specific datasheet and use appropriate controls. Biological activity and suitability must be established for the intended experimental setting.

Explore Complementary Dual-Targeting Strategies

T-Cell Engagers

CD19 / CD3e, CD3 / CD20, B7-H3 / CD3e and TYRP1 / CD3 support investigation of T-cell engagement with antigen-expressing cells.

Fluorescein / CD3e provides a format for exploring adaptor-based targeting approaches using compatible fluorescein-labelled molecules.

Checkpoint and Co-Stimulatory Targeting

PD-1 / VEGF-A combines targeting of an immune checkpoint and an angiogenic factor.

PD-L1 / CD28 and PD-L1 / OX40 provide tools for studying PD-L1-directed co-stimulatory targeting.

Innate and Adaptive Immune Checkpoints

PD-L1 / CD47 combines two targets involved in immune regulation.

This format enables investigation of interactions between adaptive checkpoint signalling and the CD47-associated “don’t eat me” pathway.

Why Use a Bispecific Format?

Combining two binding specificities within one molecule allows researchers to investigate physical bridging or coordinated dual targeting, depending on the selected antibody.

The choice of target pair and molecular format can influence biological activity. LALAPG Fc engineering is intended to reduce Fc-mediated effector interactions; it does not establish efficacy or eliminate the need for model-specific validation.

Products Available Through CliniSciences

Explore the target pairs and pack sizes currently listed in the linked CliniSciences selection.
Bispecific Antibody Base Reference Pack Sizes
Anti-Mouse CD19 / CD3e ICH1290 1, 5, 25 mg
Anti-Mouse B7-H3 / CD3e ICH1291 1, 5, 25 mg
Anti-Mouse CD3 / CD20 ICH1296 1, 5, 25 mg
Anti-Mouse TYRP1 / CD3 ICH1297 1, 5, 25 mg
Anti-Mouse Fluorescein / CD3e ICH1295 1, 5, 25 mg
Anti-Mouse PD-1 / VEGF-A ICH1289 5, 25 mg
Anti-Mouse PD-L1 / CD28 ICH1292 1, 5, 25 mg
Anti-Mouse PD-L1 / OX40 ICH1293 1, 5, 25 mg
Anti-Mouse PD-L1 / CD47 ICH1294 1, 5, 25 mg

Benefit from 25% OFF Murine Bispecific Antibodies

Promo code: Q4BISPEC25

Save 25% on all ichorbio recombinant murine bispecific antibodies until 31 December 2026.

No minimum order. No additional conditions.
Simply quote the code on your purchase order.

Explore the products →

Need help selecting a target pair or pack size? Contact the CliniSciences scientific team at tech@clinisciences.com.

For research use only. Not for use in diagnostic or therapeutic procedures.