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Reagents and instruments for immunology, cell biology and molecular biology.

Search result : 102 product found

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Unconjugated 55
AP 4
APC 4
Biotin 4
FITC 4
HRP 4
MaxLight 405 4
MaxLight 490 4
MaxLight 550 4
MaxLight 650 4
MaxLight 750 4
PE 4

human 97
mouse 6
rat 4
dog 1
monkey 1

rabbit 73
mouse 21
goat 4
human 3

Primary antibody 98
Protein/peptide 3
pcr products 1

WB 81
ELISA 29
IHC 25
FLISA 10
IF 7
FC 5

Polyclonal 71
Monoclonal 3
6F-H2 1
C40/1605 1
C40/2383 1
INSM2/4291 1
MMWT1-1 1
PAX2/1104 1
PAX8/1492 1
RMWT1-1 1
SBX10-1 1
SBX10-2R 1
SBX2-1R 1
SOX2/1791 1
SOX2/1792 1
SOX2/3169R 1
SOX2/3811R 1
SPM361 1
T8P2G4*A6 1
WLMT1-1 1
WT1/1434R 1
WT1/857 1
WT1/857 + 6F-H2 1
rSOX2/1791 1
rSOX2/1792 1
rWT1/857 1

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orb67213-100ul

Rabbit polyclonal to NR2F1.Coup (chicken ovalbumin upstream promoter) transcription factor/NR2F1 belongs to the nuclearhormone receptor family. NR2F1 binds to the ovalbumin promoter and, in conjunction with anotherprotein (S300-II) stimulates initiation of transcription. It has been shown to function in a cell-freetranscription system. NR2F1 binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif.It represses transcriptional activity of LHCG.

100ul

orb534076-20ug

SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. [RefSeq]

20ug

orb402956-20ug

SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. [RefSeq]

20ug

orb750053-20ug

SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

20ug

orb750052-20ug

SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

20ug

orb639541-20ug

Wilms Tumor is a transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. [UniProt]

20ug

orb750153-20ug

Wilms Tumor is a transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. [UniProt]

20ug

orb334997-100ug

Goat polyclonal to alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in apoptosis, angiogenesis, energy metabolism, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in tumour angiogenesis, embryonic vascularization, and pathophysiology of ischemic disease.

100ug

N0019-01L-100ul

Anti-Nanog (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, Homeobox Transcription Factor Nanog, Nanog Homeobox) Monoclonal Antibody

100ul

N0019-01B-100ul

Anti-Nanog (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, Homeobox Transcription Factor Nanog, Nanog Homeobox) Polyclonal Antibody

100ul

orb66811-100ul

Rabbit polyclonal to PRDM16.PR domain containing 16 (PRDM16) is a zinc finger transcription factor that binds to DNA andfunctions as a transcriptional regulator. It functions in the differentiation of brown adipose tissuewhich is specialized in dissipating chemical energy in the form of heat in response to cold or excessfeeding while white adipose tissue is specialized in storage of excess energy and the control ofsystemic metabolism. PRDM16 along with CEBPB regulate the differentiation of myoblasticprecursors into brown adipose cells. This gene has been implicated in a translocation event thatoccurs in a subset of acute myeloid leukemia and myelodysplastic syndrome.

100ul

N0019-01K-100ug

Anti-Nanog (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, FLJ12581, FLJ40451, Homeobox Transcription Factor Nanog, Nanog Homeobox) Polyclonal Antibody

100ug

N0019-01S-100ul

Anti-Nanog (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, FLJ12581, FLJ40451, Homeobox Transcription Factor Nanog, Nanog Homeobox) Monoclonal Antibody

100ul

N0019-01R-100ul

Anti-Nanog (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, FLJ12581, FLJ40451, Homeobox Transcription Factor Nanog, Nanog Homeobox) Monoclonal Antibody

100ul

N0019-01Z-100ug

Nanog, Recombinant, Human, aa1-305 (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, FLJ12581, FLJ40451, Homeobox Transcription Factor Nanog, Nanog Homeobox)

100ug

N0019-01Z-500ug

Nanog, Recombinant, Human, aa1-305 (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, FLJ12581, FLJ40451, Homeobox Transcription Factor Nanog, Nanog Homeobox)

500ug

N0019-02C-50ug

Nanog, Recombinant, Human, aa1-154, His-Tag (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, FLJ12581, FLJ40451, Homeobox Transcription Factor Nanog, Nanog Homeobox)

50ug

orb67115-100ul

Rabbit polyclonal to HOXA9.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are foundin clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins isspatially and temporally regulated during embryonic development. HOXA9 is part of the A cluster onchromosome 7 and encodes a sequence-specific DNA-binding transcription factor which is part of adevelopmental regulatory system that provides cells with specific positional identities on the anteriorposterioraxis. HOXA9 is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specifictranslocation event which causes a fusion between HOXA9 and NUP98 has been associated withmyeloid leukemogenesis.

100ul

orb606922-20ug

PAX2 is a member of the paired box family of transcription factors, which is required for development and proliferation of the kidney, brain, and mullerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region, which encodes a DNA-binding domain, enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system, eye, ear, and urogenital tract, and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system, including kidney, ureteric epithelium, fallopian tube epithelium, ovary and uterus. In tumors, PAX2 has been detected in renal cell carcinomas, Wilms' tumors, nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.

20ug

orb639928-20ug

SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

20ug

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