AIF1 (Allograft Inflammatory Factor 1, AIF-1, Ionized Calcium-binding Adapter Molecule 1, Protein G1, G1, IBA1) (HRP)

Referencia 029413-HRP-100ul

embalaje : 100ul

Marca : US Biological

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029413-HRP Rabbit Anti-AIF1 (Allograft Inflammatory Factor 1, AIF-1, Ionized Calcium-binding Adapter Molecule 1, Protein G1, G1, IBA1) (HRP)

Clone Type
Polyclonal
Host
mouse
Source
human
Swiss Prot
P55008
Isotype
IgG1,k
Grade
Affinity Purified
Applications
IHC WB
Crossreactivity
Hu Mo Rt
Accession #
NP_001614
Shipping Temp
Blue Ice
Storage Temp
-20°C

The allograft inflammatory factor-1 (AIF-1) is a 17kD interferon-gamma inducible Ca(2+)-binding EF-hand protein that is encoded within the HLA class III genomic region. AIF-1 is known to be identical with ionized Ca(2+)-binding adaptor 1, microglia response factor-1, and daintain. AIF-1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and the activation and function of macrophages. It is also shown to be expressed in macrophages and microglial cells in autominnume disesases such as experimental autoimmune encephalomyelitis, and neuritis and uveitis models.||Applications:|Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.||Recommended Dilutions:|Immunohistochemistry (Paraffin): Heat-induced epitope retrieval in citrate buffer, pH 6.0|Optimal dilutions to be determined by the researcher.||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. |For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. ||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG1,k|Clone No: 13A155 (20A12.1)|Host: mouse|Source: human|Concentration: As Reported |Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).|Purity: Purified by Protein G affinity chromatography.|Immunogen: Synthetic linear peptide corresponding to human AIF1.|Specificity: Recognizes human AIF1. Species Crossreactivity: mouse and rat||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Synthetic linear peptide corresponding to human AIF1.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes human AIF1. Species Crossreactivity: mouse and rat
References
1. Liu, G., et al. (2007). 40(2):95-102. 2. Del gado, F., et al. (2006). 18(6):588-593. 3. McDaniel, D.O., et al. (2010). 42(10):4235-4237.