General Info
Host: | Mouse |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-CD34 (32-290) is suitable for use in Western Blot research applications. |
Clonality: | Monoclonal |
Clone ID: | S1MR |
Conjugation: | Unconjugated |
Isotype: | IgG2bk |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | CD34 |
Gene ID: | 947 |
Uniprot ID: | CD34_HUMAN |
Immunogen Region: | 32-290 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-290 of human CD34 (P28906). |
Immunogen Sequence: | SLDNNGTATPELPTQGTFSN VSTNVSYQETTTPSTLGSTS LHPVSQHGNEATTNITETTV KFTSTSVITSVYGNTNSSVQ SQTSVISTVFTTPANVSTPE TTLKPSLSPGNVSDLSTTST SLATSPTKPYTSSSPILSDI KAEIKCSGIREVKLTQGICL EQNKTSSCAEFKKDRGEGLA RVLCGEEQADADAGAQVCSL LLAQSEVRPQCLLLVLANRT EISSKLQLMKKHQSDLKKL |
Description
Tissue Specificity | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. |
Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
Protein Name | Hematopoietic Progenitor Cell Antigen Cd34Cd Antigen Cd34 |
Database Links | Reactome: R-HSA-198933 P28906-1 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibodyAnti-Cd Antigen Cd34 antibodyAnti-CD34 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance