General Info
Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human/Pig |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-Endophilin-A1/SH3GL2, Biotinylated (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Biotin |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-0.3-1µg/mlELISA-antibody detection limit dilution 1:64000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Information
Gene Symbol: | SH3GL2 |
Gene ID: | 6456 |
Uniprot ID: | SH3G2_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_003017.1 |
Immunogen Sequence: | CSLEFPTGDSTQPN. |
Description
Function | Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes. |
Protein Name | Endophilin-A1Een-B1Endophilin-1Sh3 Domain Protein 2aSh3 Domain-Containing Grb2-Like Protein 2 |
Database Links | Reactome: R-HSA-177504Reactome: R-HSA-182971Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722Reactome: R-HSA-437239Reactome: R-HSA-6807004Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8875360 |
Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinEarly EndosomePresynapse |
Alternative Antibody Names | Anti-Endophilin-A1 antibodyAnti-Een-B1 antibodyAnti-Endophilin-1 antibodyAnti-Sh3 Domain Protein 2a antibodyAnti-Sh3 Domain-Containing Grb2-Like Protein 2 antibodyAnti-SH3GL2 antibodyAnti-CNSA2 antibodyAnti-SH3D2A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance