Antiviral agent 61

Antiviral agent 61 (compound Z40) is a potent antiviral agent. Antiviral agent 61 shows anti tomato spotted wilt virus (TSWV) activity with an EC₅₀ value of 252 μg/mL. Antiviral agent 61 increases the RNA expression of Ndufb9，COX6B，7.1.2.2，E，COX5B，Ndufs4，and SDHB，decreases the RNA expression of Ndufb7，Ndufa5，and G^[1].

453.51

C₂₂H₂₃N₅O₄S

[O-]C1=C(C(N2CCN(S(=O)(C3=CC=C(C)C=C3)=O)CC2)=O)[N+]4=CC=CC=C4N1CCC#N

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Zhang W, et al. Development of Imidazo[1,2-a]pyridines Containing Sulfonyl Piperazines as Potential Antivirals against Tomato Spotted Wilt Virus. J Agric Food Chem. 2024 Oct 23;72(42):23118-23130.  [Content Brief]