CD133 Antibody

Referencia MBS850595-0,1mg

embalaje : 0,1mg

Marca : MyBiosource


CD133 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850595

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations… More details

Product Overview

Online Datasheet in PDF
Product Name
CD133, Monoclonal Antibody
Full Product Name
CD133 Antibody
Product Gene Name
anti-CD133 antibody
Product Synonym Names
RP41; AC133; CD133; MCDR2; STGD4; CORD12
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3F10
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Specificity
Recognizes endogenous levels of TAU (pS579) protein.
Preparation and Storage
Store at 4 degree C, for long term storage, store at -20 degree C.
Molecular Weight
133kDa
OMIM
603786
3D Structure
ModBase 3D Structure for P10636
Immunogen
Synthesized peptide of human CD133 (AA: 20-36, GGQPSSTDAPK AWNYELc)

Product Categories/Family for anti-CD133 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD133 antibody
Immunohistochemistry (IHC), Flow Cytometry (FC), ELISA (EIA)

Not yet tested in other applications.
Application Notes for anti-CD133 antibody
IHC: 1:200-1:1000
FC: 1:200-1:400
ELISA: 1:10000

Flow Cytometry (FC/FACS) of anti-CD133 antibody

Figure 2: Flow cytometric analysis of Hela cells using CD133 mouse mAb (blue) and negative control (red).
Mouse Anti-CD133 Monoclonal Antibody – Cat# MBS850595

Immunohistochemistry (IHC) of anti-CD133 antibody

Figure 1: Immunohistochemical analysis of paraffin-embedded human breast cancer tissues (left) and human esophageal cancer tissues (right) using CD133 mouse mAb with DAB staining.
Mouse Anti-CD133 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS850595

Testing Data of anti-CD133 antibody

Mouse Anti-CD133 Monoclonal Antibody, Testing Data – Cat# MBS850595

Product References and Citations for anti-CD133 antibody

EFFECT OF HELICOBACTER PYLORI INFECTION ON CANCER STEM CELL MARKER (CD133) IN COLORECTAL CANCER. Mayadah Mohammed Ridha Abdul-Razzaq, Zainab Fadhel Ashoor, Wasan Abdul-ilah Bakir (2017)

Other Notes

Small volumes of anti-CD133 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD133 purchase

MBS850595 is an antibody targeting CD133. Also known as CD133 Antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD133. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
prominin-1 isoform 2
NCBI Official Synonym Full Names
prominin 1
NCBI Official Symbol
PROM1
NCBI Official Synonym Symbols
RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
UniProt Protein Name
Prominin-1
UniProt Synonym Protein Names
Antigen AC133; Prominin-like protein 1; CD_antigen: CD133
Protein Family
Prominin
UniProt Gene Name
PROM1
UniProt Synonym Gene Names
PROML1
NCBI Protein Information
prominin-1

UniProt Comments for CD133

May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD133 antibody

 Reference Product  PubMed Publications
 CD44 antibody  >8 publications with CD133 and CD44
 CD34 antibody  >3 publications with CD133 and CD34
 KDR antibody  >2 publications with CD133 and KDR
 HIF1A antibody  >2 publications with CD133 and HIF1A
 CDHR1 antibody  >2 publications with CD133 and CDHR1
 NES antibody  >1 publications with CD133 and NES
 RET antibody  >1 publications with CD133 and RET

Pathways associated with anti-CD133 antibody

 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram

Diseases associated with anti-CD133 antibody

 Disease Name  Pubmed Publications
 Colorectal Neoplasms Antibodies  >12 publications with CD133 and Colorectal Neoplasms
 Carcinoma Antibodies  >9 publications with CD133 and Carcinoma
 Adenocarcinoma Antibodies  >6 publications with CD133 and Adenocarcinoma
 Glioblastoma Antibodies  >6 publications with CD133 and Glioblastoma
 Colonic Neoplasms Antibodies  >5 publications with CD133 and Colonic Neoplasms
 Disease Models, Animal Antibodies  >5 publications with CD133 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >4 publications with CD133 and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >3 publications with CD133 and Liver Neoplasms
 Liver Diseases Antibodies  >3 publications with CD133 and Liver Diseases
 Cell Transformation, Neoplastic Antibodies  >3 publications with CD133 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-CD133 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >16 publications with CD133 and Eye
 Brain Antibodies  >14 publications with CD133 and Brain
 Liver Antibodies  >10 publications with CD133 and Liver
 Nerve Antibodies  >5 publications with CD133 and Nerve
 Intestine Antibodies  >4 publications with CD133 and Intestine
 Embryonic Tissue Antibodies  >4 publications with CD133 and Embryonic Tissue
 Lung Antibodies  >3 publications with CD133 and Lung
 Stomach Antibodies  >2 publications with CD133 and Stomach
 Testis Antibodies  >2 publications with CD133 and Testis
 Mammary Gland Antibodies  >1 publications with CD133 and Mammary Gland