CTLA-4 Antibody
Referencia orb1945375-1ml
embalaje : 1ml
Marca : Biorbyt
Contact local distributor :
Teléfono : +1 850 650 7790
CTLA-4 Antibody
Catalog Number: orb1945375
| Catalog Number | orb1945375 |
|---|---|
| Category | Antibodies |
| Description | Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) is a receptor on T helper cells that functions as an immune checkpoint and downregulator of immune responses. Mutations in CTLA-4 are associated with insulin-dependent diabetes mellitus, Hashimoto's thyroiditis, Graves' disease, systemic lupus erythematosus (SLE), celiac disease, primary biliary cirrhosis, thyroid-associated orbitopathy, multiple sclerosis, and other autoimmune diseases. The spliced variant of CTLA-4 in SLE is present in the patient's serum. Haploinsufficiency of CTLA-4 causes the immune system disorder known as CTLA-4 deficiency or CHAI disease (CTLA-4 haploinsufficiency with autoimmune infiltration). |
| Species/Host | Rabbit |
| Clonality | Monoclonal |
| Clone Number | IHC064 |
| Tested applications | IHC |
| Reactivity | Human |
| Conjugation | Unconjugated |
| Storage | Store at 2-8°C. To ensure stability, immediately replace vial back in the refrigerator after each use |
| Buffer/Preservatives | Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and < 0.1% Sodium Azide |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |