DAXX Recombinant Antibody, PE-Cy5 Conjugated
Referencia bsm-61231R-PE-Cy5
embalaje : 100uL
Marca : Bioss
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61231r-pe-cy5 |
| Product Name | DAXX Recombinant Antibody, PE-Cy5 Conjugated |
| Applications | WB, FCM |
| Reactivity | Human |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human DAXX |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 1616 |
| Swiss Prot | Q9UER7 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | Death domain-associated protein 6; Daxx; hDaxx; Fas death domain-associated protein; ETS1-associated protein 1; EAP1; DAXX; BING2; DAP6. |
| Background | Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. |
| Application Dilution | |
| WB | 1:500-2000 |
| FCM | FCM1:50-100 |