Orb507413-100mg | DLin-MC3-DMA Clinisciences

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DLin-MC3-DMA

Catalog Number	orb507413
Category	Small Molecules
Description	D-Lin-MC3-DMA(MC3) is the most potent cationic lipid that has been synthesized for Lipid nanoparticles (LNPs) to deliver the siRNA.
CAS Number	1224606-06-7
Purity	> 98%
MW	641.61
SMILES	CCCCC/C=C\C/C=C\CCCCCCCCC(OC(=O)CCCN(C)C)CCCCCCCC/C=C\C/C=C\CCCCC
Formula	C₄₃H₇₉NO₂
Hazard Information	Non-Toxic
Storage	Pure form: -20°C/3 years,4°C/2 years; In solvent: -20°C/1 month
Alternative names	1224606-06-7, D-Lin-MC3-DMA, (6Z,9Z,28Z,31Z)-Hepta
Note	For research use only
Application notes	D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
Expiration Date	12 months from date of receipt.

Ye Zeng 1, Mariona Estapé Senti 2, M Clara I Labonia 3, Panagiota Papadopoulou 1, Maike A D Brans 3, Inge Dokter 3 4, Marcel H Fens 5, Alain van Mil 3 4, Joost P G Sluijter 3 4, Raymond M Schiffelers 2, Pieter Vader 2 3, Alexander Kros 1 Fusogenic Coiled-Coil Peptides Enhance Lipid Nanoparticle-Mediated mRNA Delivery upon Intramyocardial Administration ACS Nano, 17(23), 23466–23477 (2023)