Enasidenib
Referencia MBS3601899-100mg
embalaje : 100mg
Marca : MyBiosource
Enasidenib (AG-221)
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601899An orally available, selective, potent inhibitor of mutant IDH2 with IC50s of 100-400 nM for IDH2R140Q homodimer. More details
Product Overview
Online Datasheet in PDFProduct Name
Enasidenib, Biochemical
Full Product Name
Enasidenib
Product Synonym Names
AG-221; CC-90007
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
473.375
Suitability
10mM in DMSO
Target
IDH
Receptor
IDH2
Chemical Name
2-Propanol, 2-methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1, 3, 5-triazin-2-yl]amino]
SMILES
CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O
Molecular Formula
C19H17F6N7O
CAS Number
1446502-11-9
Product Categories/Family for Enasidenib biochemical
Blood cancer; Metabolic Enzyme/Protease; Cancer
Product References and Citations for Enasidenib biochemical
1. Yen K, et al. Cancer Discov. 2017 May; 7 (5):478-493.
2. Kats LM, et al. Leukemia. 2017 Apr 11. doi: 10.1038/leu.2017.84.
3. Shih AH, et al. Cancer Discov. 2017 May; 7 (5):494-505.
2. Kats LM, et al. Leukemia. 2017 Apr 11. doi: 10.1038/leu.2017.84.
3. Shih AH, et al. Cancer Discov. 2017 May; 7 (5):494-505.
Other Notes
Small volumes of Enasidenib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Enasidenib purchase
MBS3601899 is a biochemical targeting Enasidenib.