Foliglurax monohydrochloride [2133294-96-7]
Referencia T11311-100mg
embalaje : 100mg
Marca : TargetMol
Foliglurax monohydrochloride
(Synonyms: PXT002331 (monohydrochloride)) Copy Product InfoFoliglurax monohydrochloride Antiparkinsonian effect. is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM.
Cas No. 2133294-96-7
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Foliglurax monohydrochloride Antiparkinsonian effect. is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM. |
| Targets & IC50 | mGlu4:79 nM （EC50） |
| In vitro | Foliglurax, might revolutionize the field of mGlu4 receptor drug targeting in CNS disorders.a highly selective and potent mGlu4 receptor PAM with a marked brain-penetrance feature. |
| Synonyms | PXT002331 (monohydrochloride) |
| Molecular Weight | 457.97 |
| Formula | C23H24ClN3O3S |
| Cas No. | 2133294-96-7 |
| Smiles | Cl.O\N=c1/cc(oc2ccc(CCCN3CCOCC3)cc12)-c1cc2sccc2cn1 |
| Relative Density. | 1.31g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 5 mg/mL (10.92 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||||||||||||