Human ALDH (Aldehyde Dehydrogenase, Mitochondrial) CLIA Kit

Referencia MBS2532987-96

embalaje : 96Tests

Marca : MyBiosource


ALDH (Aldehyde Dehydrogenase, Mitochondrial) (ALDH) CLIA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2532987

Intended Uses: This CLIA kit applies to the in vitro quantitative determination of ALDM concentrations in serum, plasma and other biological fluids.Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit… More details

Product Overview

Online Datasheet in PDF
Product Name
ALDH (Aldehyde Dehydrogenase, Mitochondrial), CLIA Kit
Full Product Name
Human ALDH (Aldehyde Dehydrogenase, Mitochondrial) CLIA Kit
Product Gene Name
ALDH clia kit
Product Synonym Names
ALDH2; ALDH-E2; ALDHI; Aldehyde Dehydrogenase 2
Species Reactivity
Human
Assay Type
Sandwich
Detection Range
78.125-5000pg/mL
Sensitivity
Min: 46.875pg/mL; Max: 5000pg/mL
Specificity
This kit recognizes natural and recombinant ALDM. No significant cross-reactivity or interference between ALDM and analogues was observed.
Molecular Weight
56,488 Da
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ALDH clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDH purchase

MBS2532987 is a CLIA kit targeting ALDH. Also known as Human ALDH (Aldehyde Dehydrogenase, Mitochondrial) CLIA Kit. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
aldehyde dehydrogenase, mitochondrial
NCBI Official Synonym Full Names
aldehyde dehydrogenase 2 family (mitochondrial)
NCBI Official Symbol
Aldh2
UniProt Protein Name
Aldehyde dehydrogenase, mitochondrial
UniProt Synonym Protein Names
ALDH class 2; ALDH-E2; ALDH1
Protein Family
NADP-dependent fatty aldehyde dehydrogenase
UniProt Gene Name
Aldh2
UniProt Entry Name
ALDH2_RAT
NCBI Protein Information
aldehyde dehydrogenase, mitochondrial

UniProt Comments for ALDH

ALDH2: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2011]

Protein type: Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Other Amino Acids Metabolism - beta-alanine; Carbohydrate Metabolism - propanoate; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - histidine; Lipid Metabolism - fatty acid; Mitochondrial; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - lysine degradation; Lipid Metabolism - glycerolipid; Amino Acid Metabolism - tryptophan; Secondary Metabolites Metabolism - limonene and pinene degradation; Oxidoreductase; Carbohydrate Metabolism - pyruvate; EC 1.2.1.3; Carbohydrate Metabolism - ascorbate and aldarate

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: identical protein binding; protein binding; aldehyde dehydrogenase (NAD) activity

Biological Process: response to nicotine; response to hyperoxia; ethanol catabolic process; response to lipopolysaccharide; response to testosterone stimulus; liver development; response to progesterone stimulus; response to estradiol stimulus; cellular response to hormone stimulus; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ALDH clia kit

 Reference Product  PubMed Publications
 Adh1c clia kit  >70 publications with ALDH and Adh1c
 Adh4 clia kit  >18 publications with ALDH and Adh4
 Adh7 clia kit  >16 publications with ALDH and Adh7
 Adh5 clia kit  >8 publications with ALDH and Adh5
 Adh6 clia kit  >5 publications with ALDH and Adh6

Pathways associated with ALDH clia kit

 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Biosynthesis Of Antibiotics Pathway antibodies  Biosynthesis Of Antibiotics Pathway Diagram
 Ethanol Oxidation Pathway antibodies  Ethanol Oxidation Pathway Diagram
 Fatty Acid Omega Oxidation Pathway antibodies  Fatty Acid Omega Oxidation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram

Organs/Tissues associated with ALDH clia kit

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >322 publications with ALDH and Liver
 Heart Antibodies  >136 publications with ALDH and Heart
 Brain Antibodies  >86 publications with ALDH and Brain
 Muscle Antibodies  >83 publications with ALDH and Muscle
 Artery Antibodies  >54 publications with ALDH and Artery
 Lung Antibodies  >39 publications with ALDH and Lung
 Kidney Antibodies  >23 publications with ALDH and Kidney
 Colon Antibodies  >17 publications with ALDH and Colon
 Pancreas Antibodies  >16 publications with ALDH and Pancreas
 Eye Antibodies  >11 publications with ALDH and Eye