Human FATP5 (Fatty Acid Transport Protein 5) Sandwich ELISA Kit E0008805)

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	SLC27A5
Gene ID:	10998
Uniprot ID:	S27A5_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Predominantly expressed in liver.
Post Translational Modifications
Function	May mediate the import of long-chain fatty acids (LCFA) by facilitating their transport across cell membranes. Also catalyzes the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates. Mainly functions as a bile acyl-CoA synthetase catalyzing the activation of bile acids via ATP-dependent formation of bile acid CoA thioesters which is necessary for their subsequent conjugation with glycine or taurine. Both primary bile acids (cholic acid and chenodeoxycholic acid) and secondary bile acids (deoxycholic acid and lithocholic acid) are the principal substrates. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate ((25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate or THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Plays an important role in hepatic fatty acid uptake and bile acid reconjugation and recycling but not in de novo synthesis of bile acids.
Protein Name	Long-Chain Fatty Acid Transport Protein 5 Fatp-5 Fatty Acid Transport Protein 5 Bile Acid-Coa Ligase Ba-Coa Ligase Bal Bile Acyl-Coa Synthetase Bacs Cholate--Coa Ligase Fatty-Acid-Coenzyme A Ligase - Very Long-Chain 3 Long-Chain-Fatty-Acid--Coa Ligase Solute Carrier Family 27 Member 5 Very Long-Chain Acyl-Coa Synthetase Homolog 2 Vlcs-H2 Vlcsh2 Very Long-Chain Acyl-Coa Synthetase-Related Protein Vlacs-Related Vlacsr
Database Links	Reactome: R-HSA-159418 Reactome: R-HSA-193368 Reactome: R-HSA-193775
Cellular Localisation	Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Microsome Cell Membrane
Alternative ELISA Names	Long-Chain Fatty Acid Transport Protein 5 ELISA kit Fatp-5 ELISA kit Fatty Acid Transport Protein 5 ELISA kit Bile Acid-Coa Ligase ELISA kit Ba-Coa Ligase ELISA kit Bal ELISA kit Bile Acyl-Coa Synthetase ELISA kit Bacs ELISA kit Cholate--Coa Ligase ELISA kit Fatty-Acid-Coenzyme A Ligase - Very Long-Chain 3 ELISA kit Long-Chain-Fatty-Acid--Coa Ligase ELISA kit Solute Carrier Family 27 Member 5 ELISA kit Very Long-Chain Acyl-Coa Synthetase Homolog 2 ELISA kit Vlcs-H2 ELISA kit Vlcsh2 ELISA kit Very Long-Chain Acyl-Coa Synthetase-Related Protein ELISA kit Vlacs-Related ELISA kit Vlacsr ELISA kit SLC27A5 ELISA kit ACSB ELISA kit ACSVL6 ELISA kit FACVL3 ELISA kit FATP5 ELISA kit
output

Information sourced from Uniprot.org

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