Integrin alpha 3 Polyclonal Antibody, APC-Cy7 Conjugated
Referencia bs-2093R-APC-Cy7
embalaje : 100ul
Marca : Bioss
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Teléfono : +1 850 650 7790
Integrin alpha 3 Polyclonal Antibody, APC-Cy7 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-2093R-APC-Cy7 |
| Product Name | Integrin alpha 3 Polyclonal Antibody, APC-Cy7 Conjugated |
| Applications | WB, FCM |
| Reactivity | Mouse, Pig |
| Predicted Reactivity | Human, Rat |
| Specifications | |
| Conjugation | APC-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Integrin alpha 3 |
| Immunogen Range | 976-1025/1051 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 3675 |
| Swiss Prot | P26006 |
| Subcellular location | Cell membrane |
| Synonyms | VL3A; CD49C; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3; Integrin alpha-3; CD49 antigen-like family member C; FRP-2; Galactoprotein B3; VLA-3 subunit alpha; ITGA3 |
| Background | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |