Magrolimab [2169232-81-7]
Referencia NB-64-23065-1mg
embalaje : 1mg
Marca : Neo Biotech
Magrolimab
(Synonyms: Magrolimab (anti-CD47), Hu5F9-G4) Copy Product InfoSynonyms: Magrolimab (anti-CD47), Hu5F9-G4
Catalog No. T35390 Copy Product Info
Magrolimab (Hu5F9-G4) is a humanized anti-CD47 IgG4 monoclonal antibody that exhibits antitumor activity by blocking CD47 and binding primarily to the N-terminal pyroglutamate of CD47. It can be used in combination with other compounds for the treatment of recurrent myeloma.
Cas No. 2169232-81-7
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Purity:94.52% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Magrolimab (Hu5F9-G4) is a humanized anti-CD47 IgG4 monoclonal antibody that exhibits antitumor activity by blocking CD47 and binding primarily to the N-terminal pyroglutamate of CD47. It can be used in combination with other compounds for the treatment of recurrent myeloma. |
| Synonyms | Magrolimab (anti-CD47), Hu5F9-G4 |
| Reactivity | Human |
| Verified Activity | Immobilized Human CD47 Protein (His) at 2 μg/mL (30 μL/well) can bind Magrolimab. The EC50 is 0.007668 μg/mL.  |
| Application | ELISA FCM Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | 961 |
| Uniprot ID | Q08722 |
| Target | CD47 |
| Molecular Weight | 145.74 kDa |
| Cas No. | 2169232-81-7 |
| Relative Density. | no data available |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control | Human IgG4 (S228P) kappa, Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Magrolimab (anti-CD-47)Magrolimab (antiCD47)Magrolimab (anti CD47)MagrolimabCD47anti-CD47
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Related Tags: Magrolimab chemical structure | Magrolimab molecular weight
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