Moringa oleifera Lectin (cMol)
Referencia L1366-2
embalaje : 2mg
Marca : GLYcoDiag
Moringa oleifera lectin (cMol)
| Reference | Short Name | Common Name | Inhibitory Carbohydrate | Glycans Structures Specifities |
|---|---|---|---|---|
| L1366 | cMol | Moringa oleifera | fetuin, thyroglobuline | GlcNAc, Complex carbohydrate-binding specificity |
Moringa oleifera lectin (cMol) is isolated from the seeds of plants1, 2, 3 after precipitation with ammonium sulphate. cMol lectin is an homodimeric lectin of 14 kDa and composed of
two subunits of 7 kDa linked by disulfide bonds.
cMol have a complex carbohydrate-binding specificity and recognized mainly fetuin and thyroglobulin (2). Morover, as shown in our GLYcoPROFILE platform, cMol recognizes specifically the neoglycoprotein αGlcNAc (i.e. BSA-αGlcNAc).
cMol exhibits a large range of properties as mentionned below :
- cMol agglutinates human and rabbit erythrocytes but is not blood group specific (2).
- cMol displays insecticidal activity (4).
- cMol has an anticoagulant activity (3).
- cMol has also a floculent activity which confer to the tree Moringa oleifera the name of « tree of life » in relation with the traditional use of the leaves to clarify water (3).
Applications
Validated in GLYcoPROFILE®
Features
Complex carbohydrate-binding specificity
Ordering informations
| Reference | Name | Quantity |
|---|---|---|
| L1366-10 | cMol lectin | 10 mg |
| L1366-2 | cMol lectin | 2 mg |
References
(1) Santos, A. F. S., et al. Detection of water soluble lectin and antioxydant component from Moringa oleifera seeds, Water Res., 2005, 39, 975-980.
(2) Katre, U. V., et al. Structure-activity relationship of a hemagglutinin from Moringa oleifera seeds, Int. J. Biol. Macromol., 2008, 42, 203-207.
(3) Santos, A. F. S., et al. Isolation of a seed coagulant Moringa oleifera lectin, Process Biochem., 2009, 44, 504-508.
(4) Andrade Luz, L. D., et al. Structural characterization of coagulant Moringa oleifera Lectin and its effect on hemostatic parameters., Int. J. Biol. Macromol., 2013, 58, 31-36.
| Reference | Short Name | Common Name | Inhibitory Carbohydrate | Glycans Structures Specifities | |
|---|---|---|---|---|---|
| L1222 | ABA | Agaricus Bisporus | Gal/GalNAc | Gal(β-1,3) GaINAc | |
| L1221 | AIA / Jacalin | Artocarpus intergrifolia | Gal | Galα1-6 or Galβ1-3GalNAc (T-antigen)>> lactose, more specific for T-antigen than PNA | |
| L1367 | AML | Astragalus membranaceus | Gal | Galβ | |
| L1205 | ASA | Allium sativum agglutinin | α(1,3)Man | Mannose | |
| L1889 | BanLec | Musa acuminata | Mannose, Glucose | αMan | |
| L1255 | BC2L-A | Burkholderia cenocepacia | α(1,3)Man | Mannose-containing ligands | |
| L1256 | BC2L-C | Burkholderia cenocepacia | Lewis b / Lewis Y | Fucose containing ligands | |
| L1254 | CJA | Crotalaria juncea | lactose | Gal > GalNAc | |
| L1366 | cMol | Moringa oleifera | fetuin, thyroglobuline | GlcNAc, Complex carbohydrate-binding specificity | |
| L1201 | Con A | Concanavalin A | MeαMan | α-Man, Glc |
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