NKG2A (KLRC1) (N-term) Rabbit Polyclonal Antibody

Referencia AP52396PU-N

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NKG2A (KLRC1) (N-term) Rabbit Polyclonal Antibody

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SKU
AP52396PU-N
KLRC1 Antibody (N-term)
 
Specifications
Product Data
Application IF, WB
Recommended Dilution WB:1/1000, IF:1/10-50
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KLRC1 / CD159a
Specificity This KLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KLRC1.
Buffer PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 26.3 kDa
Gene Name killer cell lectin like receptor C1
Database Link
Background Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. provided by RefSeq.
Synonyms KLRC1, NKG2A, NKG2-A/B-activating NK receptor, NK cell receptor A, CD159 antigen-like family member A, CD159a
Note Molecular Weight: 26287 Da
Reference Data
Protein Families Transmembrane
Protein Pathways Antigen processing and presentation, Graft-versus-host disease, Natural killer cell mediated cytotoxicity

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