Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Obeticholic Acid [459789-99-2]
Referencia T1789-1mL
embalaje : 1mL
Marca : TargetMol
Obeticholic Acid
Catalog No. T1789 CAS 459789-99-2
Synonyms: INT-747, 6-Ethylchenodeoxycholic acid, 6-ECDCA
Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist.
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Obeticholic Acid, CAS 459789-99-2
Description | Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist. |
Targets&IC50 | FXR:99 nM(EC50) |
Synonyms | INT-747, 6-Ethylchenodeoxycholic acid, 6-ECDCA |
Molecular Weight | 420.63 |
Formula | C26H44O4 |
CAS No. | 459789-99-2 |
Storage
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 45 mg/mL (106.98 mM)
Ethanol: 78 mg/mL (185.4 mM)
References and Literature
1. Pellicciari R, et al. J Med Chem. 2002, 45(17), 3569-3572. 2. Wang XX, et al. Am J Physiol Renal Physiol. 2009, 297(6), F1587-1596. 3. Verbeke L, et al. Hepatology. 2014, 59(6), 2286-2298.