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> p63 Protein, Human, Recombinant (His)

p63 Protein, Human, Recombinant (His)

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Referencia NB-64-49520-500ug

embalaje : 500ug

Marca : Neo Biotech


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p63 Protein, Human, Recombinant (His)

(Synonyms: Tumor protein p73-like (p73L), Tumor protein 63, Transformation-related protein 63 (TP63), TP73L, TP63, P73L, P73H, P63, p51, p40, KET, Keratinocyte transcription factor KET, Chronic ulcerative stomatitis protein (CUSP)) Copy Product Info

Synonyms: Tumor protein p73-like (p73L), Tumor protein 63, Transformation-related protein 63 (TP63), TP73L, TP63, P73L, P73H, P63, p51, p40, KET, Keratinocyte transcription factor KET, Chronic ulcerative stomatitis protein (CUSP)

Catalog No. TMPH-00842 Copy Product Info
p63 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 80.8 kDa and the accession number is Q9H3D4.
Other Forms of p63 Protein, Human, Recombinant (His):
p63 Protein, Human, Recombinant (His & GST)TMPY-02651
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For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
p63 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 80.8 kDa and the accession number is Q9H3D4.
Species
Human
Expression System
E. coli
TagN-6xHis
Accession NumberQ9H3D4
Amino AcidMNFETSRCATLQYCPDPYIQRFVETPAHFSWKESYYRSTMSQSTQTNEFLSPEVFQHIWDFLEQPICSVQPIDLNFVDEPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHEFSSPSHLLRTPSSASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMDARRNKQQRIKEEGE
Construction1-680 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsTumor protein p73-like (p73L), Tumor protein 63, Transformation-related protein 63 (TP63), TP73L, TP63, P73L, P73H, P63, p51, p40, KET, Keratinocyte transcription factor KET, Chronic ulcerative stomatitis protein (CUSP)
Research Background
Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
Chemical Properties
Molecular Weight80.8 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Tumor protein63TP 63p73Lp73 Lp 63p 51p 40CUSP
Related Tags: p63 Protein, Human, Recombinant (His) chemical structure | p63 Protein, Human, Recombinant (His) molecular weight